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7 Night Upper Mississippi River Cruise from St Louis

Ship: American Serenade
Cruise Line: American Cruise Lines
Sailed:  Monday, Sep 9, 2024 from St Louis, United States
Ended: Monday, Sep 16, 2024
The itinerary information below reflects the original day-by-day port of call schedule for the Monday, Sep 9, 2024 departure of the American Serenade. If American Cruise Lines modified this itinerary for weather or operational reasons after departing , the modified schedule would not be reflected here.
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Day by Day Summary and Map

Itinerary Map
7 Night Upper Mississippi River Cruise from St Louis
Day 1 - Monday - Sep 9, 2024
St Louis, United States
St Louis, United States      
Bus Travel      
Cruise Begins      
Alton, United States      
Alton is an idyllic town, known for its scenic limestone bluffs along the river and its rich Civil War history. The National Great Rivers Museum, located at the Melvin Price Lock and Dam, tells the stories of the Mississippi River's history, the people that rely on the river, and its many ecosystems. Hometown of jazz musician Miles Davis and Robert Wadlow, the tallest known person in history (8'11"), Alton is an inspiring and picturesque destination and the perfect place to begin your Upper Mississippi journey.
Day 2 - Tuesday - Sep 10, 2024
Hannibal, United States      
Explore Hannibal, "America's Hometown", and experience the boyhood adventures of Mark Twain. Tom Sawyer and Huck Finn come to life in this charming Missouri town, where you can run your hand along Aunt Polly's fence, explore Injun Joe's Cave, and get reacquainted with one of the world's most beloved authors. The downtown area is a thriving haven for artisans filled with specialty shops unique to Hannibal.
Day 3 - Wednesday - Sep 11, 2024
Madison, United States      
Founded as an active military outpost in 1808, Fort Madison was one of three posts established by the U.S. Army to maintain control over the newly acquired Louisiana Territory. Today, Fort Madison offers visitors a vibrant cultural scene, bucolic landscapes, and an active agri-tourism industry which celebrates the American heartland. Explore its many historic districts, where you can admire the well-preserved Victorian and Post-Renaissance architecture. Enjoy the area's museums, unique boutiques, antique shops, as well as the local breweries and wineries.
Day 4 - Thursday - Sep 12, 2024
Davenport, Iowa      
Voted one of the Most Livable Small Cities in America, Davenport is often described as a lively, active city with a hometown feel and one the largest agricultural exhibits in the world in its vicinity. Music enthusiasts will enjoy Davenport's many music festivals, including the Mississippi Valley Blues Festival, Mississippi Valley Fair, and Bix Beiderbecke Memorial Jazz Festival which is dedicated to native Jazz musician Bix Beiderbecke.
Day 5 - Friday - Sep 13, 2024
Dubuque, United States      
A "Masterpiece on the Mississippi", Dubuque is among the oldest settlements west of the Mississippi River. Take a ride on the Fenelon Place Elevator, claimed to be the world's shortest and steepest scenic railway, or try your luck in one of Dubuque's state-of-the-art casinos. View colorful Victorian mansions, stroll through the whimsical downtown area, and visit the national Mississippi River Museum and Aquarium.
Day 6 - Saturday - Sep 14, 2024
Winona, United States      
Step into 19th-century America in Winona, Minnesota, located in the picturesque bluff country on the Mississippi River. Explore this vibrant small town with the perfect blend of urban edge and old world charm. From rolling fields of prairie flowers to some of the most architecturally important buildings in Minnesota, enjoy all there is to see and do here.
Day 7 - Sunday - Sep 15, 2024
Red Wing, United States      
Nestled among the scenic bluffs of the upper Mississippi River, Red Wing's beauty has inspired artists, writers, and musicians for over 150 years, delivering a diverse blend of arts, entertainment, and activities for your pleasure. Enjoy a show at the historic Sheldon Theatre of Performing Arts or observe the beauty of nature at one of Red Wing's 38 parks.
Day 8 - Monday - Sep 16, 2024
Red Wing, United States      
Cruise Ends      
Bus Travel      
St Paul, United States      
Your amazing cruise into the Heartland will disembark in Red Wing, MN. From there, you will be transported to St. Paul Airport. Or if you choose, stay an extra day or two in this vibrant river town.