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7 Night Upper Mississippi River Cruise from Alton, Illinois

Ship: American Serenade
Cruise Line: American Cruise Lines
Sailed:  Thursday, Sep 21, 2023 from Alton, Illinois, United States
Ended: Thursday, Sep 28, 2023
The itinerary information below reflects the original day-by-day port of call schedule for the Thursday, Sep 21, 2023 departure of the American Serenade. If American Cruise Lines modified this itinerary for weather or operational reasons after departing , the modified schedule would not be reflected here.
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Day by Day Summary and Map

Day 1 - Thursday - Sep 21, 2023
Alton, United States      
Nestled neatly beneath towering limestone bluffs, the port of Alton, Illinois, offers easy access to St. Louis and area attractions, including the National Great Rivers Museum, which tells stories of the Mississippi River's rich history, the people that rely on the river, and its many ecosystems. Discover the area's extensive history at the excellent Missouri History Museum in the city's lovely Forest Park, the site of the legendary 1904 World's Fair. Or stand in awe at the Cathedral Basilica with its mosaic tile interior which rivals the cathedrals of Europe. Celebrate the United States western expansion and those who made it possible at the recently renovated Gateway Arch monument and the innovative and interactive underground museum.
Day 2 - Friday - Sep 22, 2023
Hannibal, United States      
Explore Hannibal, "America's Hometown", a mere block from the ship, where Mark Twain's home and museum illuminate the events that shaped his life and career. Elements of his childhood adventures were woven into classics like The Adventures of Tom Sawyer and The Adventures of Huckleberry Finn. Run your hand along Aunt Polly's fence, explore Injun Joe's Cave, and get reacquainted with one of the world's most beloved authors. Explore other nearby museums and the charming downtown Main Street with unique shops, art galleries, and tasty temptations.
Day 3 - Saturday - Sep 23, 2023
Madison, United States      
Walk a few steps from the ship to the impressive replica of Fort Madison. A historic U.S. Army fort built in 1808 to maintain control over the newly acquired Louisiana Territory, it was an important part of the western expansion. Today, Fort Madison offers visitors a vibrant cultural scene, bucolic landscapes, and an active agritourism industry that celebrates the American heartland. Visit a local farm to learn about cheese-making, explore a corn maze, and enjoy a wagon ride. Discover the town's many historic districts, where you can admire well-preserved Victorian and Neo-Renaissance architecture. Visit the area's museums, unique boutiques, antique shops, as well as the local breweries and wineries.
Day 4 - Sunday - Sep 24, 2023
Davenport, Iowa      
Davenport is your largest cruise port between St. Louis and St. Paul and one of the four "Quad Cities" that combine into a larger metro area. The first railroad to reach the Mississippi River connected Chicago to Rock Island, Illinois, across the river. The area features diverse attractions ranging from grand historic mansions lining the river, renowned museums, rich Native American history, and the largest agricultural exhibit in the world. Be enlightened by the region's history, culture, and environment at the Smithsonian-affiliated Putnam Museum and Science Center. Learn how American ingenuity powers the Midwest's ability to feed the nation at the expansive John Deere Pavilion as you amble through interactive exhibits of vintage and modern high-tech equipment that reveal the evolution of inventions that revolutionized American farming.
Day 5 - Monday - Sep 25, 2023
Dubuque, United States      
A "Masterpiece on the Mississippi", Dubuque is among the oldest settlements west of the Mississippi River and continues today as a primary commercial, industrial, educational, and cultural center for this region. From the ship, it's a short walk to a cruise highlight at the incredible complex of the Smithsonian-affiliated National Mississippi River Museum & Aquarium. View colorful Victorian mansions on a stroll through the quaint downtown area, take a ride on the world's shortest and steepest scenic railway, or try your luck in one of Dubuque's state-of-the-art casinos. Visit one of the oldest catholic churches in the city and enjoy the lovely landscapes of the Dubuque Arboretum & Botanical Gardens.
Day 6 - Tuesday - Sep 26, 2023
Winona, United States      
Winona welcomes you with the perfect blend of modern development and old river town charm. From rolling fields of flowers to some of the most architecturally important buildings in Minnesota, enjoy a carefully crafted selection of excursions that lead you through the most intriguing sites Winona has to offer. Explore a variety of history and art museums and admire historic homes, while listening to captivating stories told by a local guide. Board a self-exploration shuttle which takes you into the heart of downtown to learn, shop, eat, and stroll at your leisure.
Day 7 - Wednesday - Sep 27, 2023
Red Wing, United States      
Below the forested limestone bluffs of the upper Mississippi and along a narrow section of a river channel, Red Wing snuggles among dozens of enchanting city parks. The town's beauty has inspired artists, writers, and musicians for over 150 years, delivering a diverse blend of arts, entertainment, and activities for your pleasure. Explore the historic Sheldon Theatre of Performing Arts, the home of the famous Red Wing Shoes, and the Pottery Museum, or ride up the bluff for a remarkable view. Visit the National Eagle Center to learn more about these incredible creatures with the added thrill of admiring them up close.
Day 8 - Thursday - Sep 28, 2023
St Paul, United States
St Paul, United States      
Enjoy easy access to the Minneapolis/St. Paul airport or extend your stay to further explore this enchanting area. The Twin Cities offer world-class art galleries, museums, and live performances. St. Paul's Summit Avenue showcases gorgeous historic mansions built in the late 1800s. The enormous Mall of America includes more than 500 stores and an indoor waterpark and theme park. View gorgeous panoramas of the city from Mounds Park and cherish the enchantment of Minnehaha Falls with its 53-foot cascade.