Back
iCruise.com iCruise.com

8 Night Upper Mississippi and Land Tour

From St Paul to St Louis

American Serenade

American Cruise Lines
4 Stars
  • Cruise #: 14139180
  • Departs: Fri, Jul 3, 2026
  • Returns: Sat, Jul 11, 2026
    Track this Cruise and Get Price Alerts.
    Balcony $5,635
    Suite $7,795
    *Prices are per person based on double occupancy
    Includes taxes & fees
    Tap the "Request A Quote" button to get a quote include unadvertised prices including Senior, Military and Resident promotions.
    Request A Quote

    Itinerary Summary

    Day by Day Details

    Land Segment of Itinerary

    Friday - Jul 3, 2026
    Day
    1
    St Paul, United States
    • St Paul, United States
    In St. Paul, a stroll down Summit Avenue unveils a captivating array of historic mansions, each with its own story to tell from the late 1800s. For a shopping extravaganza like no other, venture into the vast expanse of the Mall of America, boasting over 500 stores alongside an indoor water park and theme park. And don't miss the opportunity to visit the natural wonder of Minnehaha Falls, where a 53-foot cascade cascades into a serene oasis, enveloping visitors in its enchanting charm. ...
    Read More

    Land Segment of Itinerary

    Saturday - Jul 4, 2026
    Day
    2
    St Paul, United States
    • St Paul, United States
    • Bus Travel

    Cruise Segment of Itinerary

    Day 2 - Saturday - Jul 4, 2026
    Day
    2
    Cruise Begins
    • Cruise Begins
    • Red Wing, United States
    A day on the river is not a day lost. Grab a book, a friend, a game, or an onboard expert and take the day as it comes as we navigate the Mississippi from Hannibal, MO, to Muscatine, IA. Engage in curated activities, from destination-focused enrichment programs led by esteemed guest speakers to stimulating Art and App-titude Classes and group Cooking Demonstrations. Embrace spirited camaraderie with Mixology sessions, Trivia challenges, and Game Shows. ...
    Read More
    Sunday - Jul 5, 2026
    Day
    3
    • La Crosse, United States
    Step into 19th-century America in La Crosse, situated on the banks of three captivating rivers. Riverside Park offers a spectacle of beautiful gardens, an outdoor performance center, and inspiring sculptures that ignite the imagination. Gaze out from the heights of Grandad Bluff, a 600-foot-high vantage point that provides a breathtaking, panoramic view over the entire city. Accompanied by a local expert, explore the city's evolution from its riverboat boomtown days, through the roaring '20s, to the contemporary challenges and opportunities it faces today. This is La Crosse-a city where history meets the modern world, inviting you to explore its continued evolution. ...
    Read More
    Monday - Jul 6, 2026
    Day
    4
    • Cruising the Mississippi River, United States
    With the wide upper Mississippi River before you, relish the quiet sounds of the river. Relax on your private balcony and watch the riverbanks come to life with a vast array of wildlife that call these shores home or learn the stories of the area around you from the onboard expert. The day is yours, wander to the sun deck for the best views of the winding river. Enjoy live music, but wherever you roam, don't forget to stop by the restaurant for freshly baked cookies at 3 pm daily. ...
    Read More
    Tuesday - Jul 7, 2026
    Day
    5
    • Dubuque, United States
    Dubuque is a true masterpiece along the Mississippi River. As one of the oldest settlements west of the great river, Dubuque wears its history proudly while staying a modern hub for commerce, industry, education, and culture. Step off the ship and into the renowned National Mississippi River Museum & Aquarium, a mesmerizing complex that promises to captivate your senses. Wander through the charming streets adorned with picturesque Victorian mansions, feel the thrill of riding the world's shortest and steepest scenic railway, or visit one of its oldest Catholic churches, and then the Dubuque Arboretum & Botanical Gardens. ...
    Read More
    Wednesday - Jul 8, 2026
    Day
    6
    • Davenport, Iowa
    Step into Davenport, the largest cruise port between St. Louis and St. Paul, a key city within the dynamic "Quad Cities" that merge into an extensive metro area. History marked its presence here when the first railroad to cross the Mississippi River connected Chicago to Rock Island, Illinois, just across the river. The area hosts a diverse array of attractions, from grand historic mansions along the riverbank to acclaimed museums and significant Native American historical sites, alongside the largest agricultural exhibit in the world. At the Smithsonian-affiliated Putnam Museum, gain insights into the region's diverse history, culture, and natural environment. Visit the expansive John Deere Pavilion, where the spirit of American ingenuity shines through interactive displays. Stroll through exhibits of both vintage and modern high-tech equipment that illustrate the evolution of technologies that have transformed American farming. Here, the narrative of agricultural advancement unfolds, highlighting the Midwest's crucial role in feeding the nation. ...
    Read More
    Thursday - Jul 9, 2026
    Day
    7
    • Hannibal, United States
    Welcome to Hannibal, Missouri, a charming riverside town brimming with character. At the heart of Hannibal lies the legacy of its most famous resident, Mark Twain, whose childhood adventures served as the inspiration for some of literature's most beloved characters. Explore Twain's boyhood home, a beautifully preserved white clapboard house where the author spent his formative years. Nearby, the Mark Twain Boyhood Home & Museum offers a fascinating glimpse into Twain's life and works, including original manuscripts, rare artifacts, and interactive exhibits that bring his stories to life in vivid detail. But Hannibal is more than just a literary landmark. Take a leisurely stroll down Main Street, where charming boutiques, art galleries, and antique shops beckon with unique finds and friendly smiles. Don't miss the Rockcliffe Mansion, registered as a historic home, and has breathtaking views of the Mississippi River while you learn about the history of Hannibal. ...
    Read More
    Friday - Jul 10, 2026
    Day
    8
    • Alton, Illinois, United States
    Tucked away beneath the limestone bluffs lies the charming port of Alton, Illinois, serving as a gateway to endless adventures in St. Louis and beyond. But before you set off on your escapades, start your journey with a visit to the captivating National Great Rivers Museum. Learn about the fascinating tales of the mighty Mississippi River, exploring its extensive history, the communities it sustains, and the diverse ecosystems it nurtures. ...
    Read More
    Saturday - Jul 11, 2026
    Day
    9
    • Alton, Illinois, United States
    • Cruise Ends

    Land Segment of Itinerary

    Day 9 - Saturday - Jul 11, 2026
    Day
    9
    • Bus Travel
    • St Louis, United States
    Enjoy breakfast onboard the ship as you prepare for your journey home. Reflect upon the memorable experiences and the new friendships forged during your time with American Cruise Lines.


    Get FREE Price Alerts

    Subscribe to our weekly cruise deals email and enjoy FREE price change alerts and updates for this cruise and others like it.

    We promise to protect your privacy and personal data. You can review our privacy policy here.

    Complete the form below and we will send this cruise and a message to your friends on your behalf.

    Enter up to 5 emails separated by commas:

    Your First Name

    Your Last Name

    Your Email Address:

    Optional Message to Your Friend(s):

    Send Email

    Please enter your email address to Add to Favorites. You can then access this cruise from other devices.


    Email Address:

    Save to Favorites

    This cruise line does not offer live online pricing. Please complete the form below for a quote on this cruise or call for rates.


    How many are traveling
    Adults (Age 18 and over)
    Kids (6 months to 17 years)
    First NameLast NameState of Residence

    Phone NumberEmail AddressAny special request or comments?

    Submit Request >